Perinatal Autopsy Finding in OEIS Complex Associated with Other Congenital Anomalies

OEIS complex is one of the congenital anomalies not compatible with life. It comprises of omphalocele, exstrophy of the cloaca, imperforate anus and spinal defects with incidence of 1:100,000 live births. It can be associated with other anomalies of urinary tract, genital tract, skeletal defects variably. Diagnosis can be done prenatally by ultrasonography. We present a case of OEIS complex with other associated congenital anomalies like imperforate anus, absent external genitalia, gonads, appendix with single kidney, meningocele and limb deformity in the form of talipesequinovalgus in a 29 weeks foetus. It was delivered vaginally by a fifth gravida female without any risk factors and all the four siblings are leading normal post-natal life.